Baclofen in the treatment of stiff-man syndrome

Ann Neurol. 1981 May;9(5):511-2. doi: 10.1002/ana.410090516.


Baclofen, 90 mg daily, was given to a patient with stiff-man syndrome diagnosed by electromyography and clinical criteria. The patient, bedridden for three years, experienced a decrease in rigidity, cramping, stiffness, and spasm and was able to walk on the thirtieth day of treatment.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Baclofen / therapeutic use*
  • Female
  • Humans
  • Muscle Rigidity / drug therapy*
  • Muscle Spasticity / drug therapy*
  • Syndrome


  • Baclofen