Principles of selective inactivation of viral genome. I. UV-induced inactivation of influenza virus

Arch Virol. 1981;68(3-4):239-47. doi: 10.1007/BF01314577.


Photosensitivity of infectious, haemagglutinating and neuraminidase activities of influenza virus has been determined experimentally. The photosensitivity of infectious activity of type B (strain Hongkong/8/73) influenza virus ws found to be higher than that of type A strains NIB-4 (N3N2-3), Leningrad/399/76 (H3N2-3) and NIB-6 (H1N1). The data obtained may be used for the determination of conditions of UV-irradiation for preparation of UV-inactivated antiviral vaccines.

Publication types

  • Comparative Study

MeSH terms

  • Hemagglutination Tests
  • Neuraminidase / metabolism
  • Orthomyxoviridae / enzymology
  • Orthomyxoviridae / pathogenicity
  • Orthomyxoviridae / radiation effects*
  • Species Specificity
  • Ultraviolet Rays


  • Neuraminidase