Should clearance be normalised to body surface or to lean body mass?

Br J Clin Pharmacol. 1981 May;11(5):523-6. doi: 10.1111/j.1365-2125.1981.tb01163.x.
No abstract available

MeSH terms

  • Aging
  • Body Surface Area*
  • Body Weight*
  • Child
  • Child, Preschool
  • Creatinine / metabolism
  • Female
  • Gentamicins / metabolism
  • Half-Life
  • Humans
  • Infant
  • Infant, Newborn
  • Male
  • Metabolic Clearance Rate
  • Pharmaceutical Preparations / metabolism*

Substances

  • Gentamicins
  • Pharmaceutical Preparations
  • Creatinine