Primary demyelinating disease simulating glioma of the corpus callosum: report of three cases

J Neurosurg. 1981 Oct;55(4):620-4. doi: 10.3171/jns.1981.55.4.0620.


Computerized tomography (CT) has made it easier to distinguish tumoral from nontumoral diseases of the central nervous system. In the presence of mass effect, however, this distinction may be difficult or impossible to make. Primary demyelinating disease may occasionally present as a focal cerebral mass. The authors report three cases of primary demyelinating disease of the brain involving the corpus callosum and periventricular white matter and associated with mass effect, which proved difficult to differentiate from infiltrating "butterfly" gliomas.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Brain Diseases / diagnostic imaging*
  • Brain Neoplasms / diagnostic imaging*
  • Corpus Callosum / diagnostic imaging*
  • Demyelinating Diseases / diagnostic imaging*
  • Diagnosis, Differential
  • Female
  • Glioma / diagnostic imaging*
  • Humans
  • Male
  • Tomography, X-Ray Computed