Cholecystokinin and enkephalin levels following ethanol administration in rats

Peptides. 1981 Summer;2(2):223-6. doi: 10.1016/s0196-9781(81)80038-1.

Abstract

Using radioimmunoassay, cholecystokinin and enkephalin levels were determined in the brain and gut of rats following ethanol administration. Acute or chronic administration of ethanol did not affect the cholecystokinin or enkephalin content of rat brain cortex, hypothalamus, striatum or proximal small bowel. This contrasts with the reports of altered levels of several classical neurotransmitters following ethanol administration.

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Animals
  • Brain / drug effects
  • Brain / metabolism*
  • Cholecystokinin / metabolism*
  • Endorphins / metabolism*
  • Enkephalins / metabolism*
  • Ethanol / pharmacology*
  • Intestine, Small / drug effects
  • Intestine, Small / metabolism*
  • Kinetics
  • Male
  • Organ Specificity
  • Radioimmunoassay
  • Rats

Substances

  • Endorphins
  • Enkephalins
  • Ethanol
  • Cholecystokinin