Immunoglobulin E antibodies that crossreact with vegetable foods, pollen, and Hymenoptera venom

J Allergy Clin Immunol. 1981 Nov;68(5):356-64. doi: 10.1016/0091-6749(81)90133-0.


IgE in some human sera reacted with an antigen present in a large number of unrelated foods: potato, spinach, wheat, buckwheat, peanut, honey and others. The antigen, which was periodate-sensitive and heat-stable, was also found in pollen. Even more surprisingly, these antibodies often reacted in vitro with bee and vespid venom and were sometimes apparently induced by Hymenoptera stings.

MeSH terms

  • Adolescent
  • Adult
  • Animals
  • Antigen-Antibody Reactions
  • Bee Venoms / immunology
  • Binding Sites, Antibody
  • Cross Reactions*
  • Female
  • Guinea Pigs
  • Humans
  • Hymenoptera
  • Immunoglobulin E / biosynthesis*
  • Pollen / immunology*
  • Rabbits
  • Radioallergosorbent Test
  • Vegetables*
  • Wasp Venoms / immunology


  • Bee Venoms
  • Wasp Venoms
  • Immunoglobulin E