Inactivation of netilmicin by carbenicillin

Infection. 1978;6(5):241. doi: 10.1007/BF01642317.

Abstract

Netilmicin was added to human serum and stored at various temperatures and carbenicillin concentrations prior to bioassay. Inactivation of netilmicin increased with temperature and carbenicillin concentration. The order of inactivation of aminoglycosides was: tobramycin greater than gentamicin, netilmicin greater than amikacin.

MeSH terms

  • Amikacin / pharmacology
  • Animals
  • Carbenicillin / pharmacology*
  • Drug Interactions
  • Gentamicins / pharmacology*
  • In Vitro Techniques
  • Netilmicin / pharmacology*
  • Tobramycin / pharmacology

Substances

  • Gentamicins
  • Netilmicin
  • Amikacin
  • Carbenicillin
  • Tobramycin