Antimicrobial activity of phenolic constituents of Magnolia grandiflora L

J Pharm Sci. 1981 Aug;70(8):951-2. doi: 10.1002/jps.2600700833.


Three phenolic constituents of Magnolia grandiflora L. were shown to possess significant antimicrobial activity using an agar well diffusion assay. Magnolol, honokiol, and 3.5'-diallyl-2'-hydroxy-4-methoxybiphenyl exhibited significant activity against Gram-positive and acid-fast bacteria and fungi. The minimum inhibitory concentrations were determined for each compound using a twofold serial dilution assay.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anti-Bacterial Agents
  • Anti-Infective Agents* / isolation & purification
  • Bacteria / drug effects
  • Drug Evaluation, Preclinical
  • Fungi / drug effects
  • Microbial Sensitivity Tests
  • Phenols / pharmacology*
  • Plant Extracts / pharmacology
  • Plants / analysis*


  • Anti-Bacterial Agents
  • Anti-Infective Agents
  • Phenols
  • Plant Extracts