Volume of polycystic kidneys during reduction of renal function

Urol Radiol. 1981;3(2):85-9. doi: 10.1007/BF02927815.


Total renal volume was measured by CT scanning in 43 patients with the adult form of polycystic kidney disease whose 24h endogenous creatinine clearance ranged from 8 to 130 ml/min. The total volume of the 2 kidneys increased from 1,212 (SD +/- 411) cm3 in patients with normal renal function to 2,053 (SD +/-698) cm3 in patients with severely decreased function, as compared to 497 (SD +/- 58) cm3 in persons without evidence of renal disease. Despite progression of the disease, the mean difference in size between the 2 kidneys remained constant and was significant only in patients with well-preserved renal function. In 23 of the 43 patients hepatic cysts and in 2 patients pancreatic cysts were demonstrable by CT scanning.

MeSH terms

  • Adolescent
  • Adult
  • Age Factors
  • Aged
  • Female
  • Humans
  • Kidney / diagnostic imaging
  • Kidney / physiopathology
  • Kidney Function Tests
  • Male
  • Middle Aged
  • Polycystic Kidney Diseases / diagnostic imaging*
  • Polycystic Kidney Diseases / pathology
  • Polycystic Kidney Diseases / physiopathology
  • Tomography, X-Ray Computed*