Activity of adenosine deaminase allelic forms in intact erythrocytes and in lymphocytes

Ann Hum Genet. 1981 Feb;45(1):15-9. doi: 10.1111/j.1469-1809.1981.tb00301.x.


The distribution of ADA activity has been studied for ADA 1 and ADA 2-1 individuals in intact and lysed erythrocytes and in lymphocyte lysates. ADA activity in intact RBC is 20-30% lower than in lysates, in lymphocytes it is 10 times higher. The difference between ADA 1 and ADA 2-1 mean enzyme activities which we previously described in RBC lysates has been found also in intact RBC and in lymphocyte lysates.

MeSH terms

  • Adenosine Deaminase / blood*
  • Adenosine Deaminase / genetics
  • Adult
  • Alleles
  • Erythrocytes / enzymology*
  • Female
  • Hemolysis
  • Humans
  • Lymphocytes / enzymology*
  • Male
  • Nucleoside Deaminases / blood*


  • Nucleoside Deaminases
  • Adenosine Deaminase