Goldfish brain extract induces aggregation of acetylcholine receptors on cultured myotubes: increased activity following optic nerve axotomy

Neurosci Lett. 1981 Dec 11;27(2):165-70. doi: 10.1016/0304-3940(81)90262-7.

Abstract

Acetylcholine receptor aggregation-inducing factor(s) is found in goldfish brain extract. The specific activity of the factor(s) is increased during goldfish optic nerve regeneration and peaks at 8 days following the nerve axotomy. It is therefore speculated that this activity is associated with the goldfish visual system plasticity.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Animals
  • Axons / physiology*
  • Brain / physiology*
  • Cells, Cultured
  • Goldfish
  • Kinetics
  • Muscles / drug effects
  • Muscles / physiology*
  • Optic Nerve / physiology*
  • Rats
  • Receptors, Cholinergic / drug effects
  • Receptors, Cholinergic / physiology*
  • Tissue Extracts / pharmacology*

Substances

  • Receptors, Cholinergic
  • Tissue Extracts