Two cases of chlamydial pelvic inflammatory disease (PID) are presented. Each was clinically assessed and followed by laboratory methods now available to practitioners. These patients presented with vaginal discharge and chronic abdominal pain. They initially had positive chlamydia cultures which became negative after treatment with tetracycline. Their chlamydia titers increased throughout the course of their disease and treatment. Patient two is a case of the Fitz-Hugh-Curtis syndrome due to chlamydia. The importance of this disease in adolescents and the potential sequelae and complications of chlamydial PID are discussed.