Kynurenine formamidase inhibition as a possible mechanism for certain teratogenic effects of organophosphorus and methylcarbamate insecticides in chicken embryos

Biochem Pharmacol. 1977 Dec 1;26(23):2251-8. doi: 10.1016/0006-2952(77)90288-x.
No abstract available

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Amidohydrolases / antagonists & inhibitors*
  • Animals
  • Arylformamidase / antagonists & inhibitors*
  • Carbamates*
  • Chick Embryo
  • Chickens
  • In Vitro Techniques
  • Insecticides / pharmacology*
  • Kynurenine
  • Liver / enzymology
  • Male
  • Mice
  • NAD / analysis
  • Organophosphorus Compounds*
  • Structure-Activity Relationship
  • Teratogens / pharmacology*
  • Tryptophan / metabolism
  • Tryptophan Oxygenase / metabolism

Substances

  • Carbamates
  • Insecticides
  • Organophosphorus Compounds
  • Teratogens
  • NAD
  • Kynurenine
  • Tryptophan
  • Tryptophan Oxygenase
  • Amidohydrolases
  • Arylformamidase