Surgical management of pulmonary disease due to Mycobacterium avium-intracellulare

Rev Infect Dis. 1981 Sep-Oct;3(5):1064-7. doi: 10.1093/clinids/3.5.1064.


Of 131 patients with pulmonary infections due to Mycobacterium avium-intracellulare, 124 had excisional surgery plus chemotherapy. Seven had definitive thoracoplasties. Postoperative complications of various degrees developed in 24% of those who had surgery. Bronchopleural fistulae requiring thoracoplasties occurred in seven patients. Nine patients died in the postoperative period. The sputum of 93% of the patients became negative for M. avium-intracellulare, and 5% of the patients had bacteriologic relapse. Only two of the 122 patients who survived surgery died from progressive pulmonary infection due to M. avium-intracellulare.

MeSH terms

  • Adult
  • Aged
  • Aminosalicylic Acid / therapeutic use
  • Female
  • Follow-Up Studies
  • Humans
  • Male
  • Middle Aged
  • Mycobacterium Infections, Nontuberculous / surgery
  • Mycobacterium avium / isolation & purification
  • Pneumonectomy
  • Sputum / microbiology
  • Tuberculosis, Pulmonary / drug therapy
  • Tuberculosis, Pulmonary / etiology
  • Tuberculosis, Pulmonary / microbiology
  • Tuberculosis, Pulmonary / surgery*


  • Aminosalicylic Acid