Diffuse intrapulmonary hemorrhage, renal failure and a systemic vasculitis. A case report and review of the literature

Am J Med. 1980 Feb;68(2):299-304. doi: 10.1016/0002-9343(80)90371-x.


A 63 year old women was hospitalized with massive hemoptysis, anemia and renal failure. Despite intensive supportive care, she died soon after admission. Autopsy revealed diffuse necrotizing alveolitis, rapidly progressive glomerulonephritis and a systemic vasculitis. Massive intrapulmonary hemorrhage with hemoptysis is an unusual complication of a systemic vasculitis. The case is discussed and the literature reviewed.

Publication types

  • Case Reports

MeSH terms

  • Acute Kidney Injury / etiology*
  • Anemia / etiology
  • Anti-Glomerular Basement Membrane Disease / diagnosis
  • Diagnosis, Differential
  • Female
  • Glomerulonephritis / etiology
  • Granulomatosis with Polyangiitis / diagnosis
  • Hemoptysis / etiology*
  • Humans
  • Kidney / pathology
  • Lung / pathology
  • Middle Aged
  • Vasculitis / complications*
  • Vasculitis / diagnosis
  • Vasculitis / pathology