Acute exercise stress in the pregnant ewe

Am J Obstet Gynecol. 1980 Feb 15;136(4):489-94. doi: 10.1016/0002-9378(80)90676-6.


In the near-term pregnant ewe, acute treadmill exercise produced significant changes in maternal and fetal parameters only with the onset of maternal exhaustion which was unrelated to the degree or duration of maternal exercise. With exercise to exhaustion the rate of both uterine and umbilical blood flow fell but uterine and umbilical oxygen uptakes were unchanged. Although maternal lacticemia developed and fetal PO2 fell no excess lactate was produced by the uteroplacental tissues or fetus. The increase in maternal heart rate during exercise was directly related to the decrease in uterine blood flow.

MeSH terms

  • Animals
  • Carbon Dioxide / blood
  • Female
  • Fetal Heart / physiology
  • Heart Rate
  • Lactates / blood
  • Oxygen / blood
  • Physical Exertion*
  • Pregnancy
  • Pregnancy, Animal*
  • Pyruvates / blood
  • Regional Blood Flow
  • Sheep / physiology*
  • Stress, Physiological / physiopathology*
  • Umbilical Veins / physiology
  • Uterus / blood supply


  • Lactates
  • Pyruvates
  • Carbon Dioxide
  • Oxygen