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, 61 (1), 59-60

Progressive Retinal Atrophy in the Samoyed

  • PMID: 7366567

Progressive Retinal Atrophy in the Samoyed

P F Dice 2nd. Mod Vet Pract.


In Samoyeds 2-5 years old, progressive retinal atrophy was evidenced ophthalmoscopically by peripheral tapetal hyperreflectivity and vascular attenuation, with marked generalized retinal thinning and vascular attenuation at 5-8 years. Pupil response remained active until late in the disease. Histologically, early retinal development was normal, with lesion onset paralleling that of ERG abnormalities. Pedigree examination and test-breeding results were compatible with simple autosomal recessive inheritance.

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