Familial functional antithrombin III deficiency

Scand J Haematol. 1980 Feb;24(2):105-9. doi: 10.1111/j.1600-0609.1980.tb02352.x.

Abstract

A family with a tendency to thrombosis and decreased antithrombin III (AT III) activity in plasma, but normal immunoreactive AT III is reported. 7 members of the family had the AT III defect, 4 of whom have had thrombotic episodes. The importance of biological determination of AT III when studying patients with recurrent thrombotic episodes is emphasized.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Antithrombin III / analysis
  • Antithrombin III / genetics
  • Antithrombin III Deficiency*
  • Female
  • Humans
  • Male
  • Middle Aged
  • Pedigree
  • Pulmonary Embolism / blood
  • Pulmonary Embolism / complications
  • Pulmonary Embolism / genetics
  • Recurrence
  • Thrombophlebitis / blood
  • Thrombophlebitis / complications
  • Thrombophlebitis / genetics*
  • Warfarin

Substances

  • Warfarin
  • Antithrombin III