Abstract
A family with a tendency to thrombosis and decreased antithrombin III (AT III) activity in plasma, but normal immunoreactive AT III is reported. 7 members of the family had the AT III defect, 4 of whom have had thrombotic episodes. The importance of biological determination of AT III when studying patients with recurrent thrombotic episodes is emphasized.
MeSH terms
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Adult
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Antithrombin III / analysis
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Antithrombin III / genetics
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Antithrombin III Deficiency*
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Female
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Humans
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Male
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Middle Aged
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Pedigree
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Pulmonary Embolism / blood
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Pulmonary Embolism / complications
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Pulmonary Embolism / genetics
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Recurrence
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Thrombophlebitis / blood
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Thrombophlebitis / complications
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Thrombophlebitis / genetics*
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Warfarin
Substances
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Warfarin
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Antithrombin III