Adult-onset foveomacular pigment epithelial dystrophy

Am J Ophthalmol. 1980 May;89(5):680-91. doi: 10.1016/0002-9394(80)90288-3.


Thirty-three pateints had adult-onset foveomacular dystrophy. The macular lesions typically resulted in a mild to moderate decrease in vision and appeared as small, yellow, bilateral, slightly elevated, pigment epithelial lesions with areas of hyperpigmentation. The characteristic finding on fluorescein angiography was a ring of hyperfluorescence surrounding an area of hypofluorescence. The electro-oculograms were either normal or slightly subnormal in most cases. This dystrophy appears to have an autosomal dominant transmission.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Aged
  • Electrooculography
  • Electroretinography
  • Eye Diseases / complications
  • Female
  • Fluorescein Angiography
  • Fovea Centralis
  • Humans
  • Macular Degeneration / complications
  • Macular Degeneration / diagnosis*
  • Macular Degeneration / diagnostic imaging
  • Male
  • Middle Aged
  • Pigment Epithelium of Eye*
  • Pigmentation Disorders / complications
  • Radiography
  • Visual Acuity