Abstract
Charged polymers, known to alter cell surface characteristics, reversibly inhibit the intercellular communication required in kidney tubule induction. This effect seems to be a function of their charge density. It is suggested that this effect is due to the formation of a molecular barrier between the interacting cell surfaces.
MeSH terms
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Animals
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Cell Differentiation / drug effects*
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Chondroitin Sulfates / pharmacology
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Culture Techniques
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Dextrans / pharmacology
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Embryonic Induction / drug effects*
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Heparin / pharmacology
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Kidney Tubules / drug effects*
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Kidney Tubules / embryology
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Kidney Tubules / metabolism
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Mice
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Polylysine / pharmacology
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Polymers / pharmacology*
Substances
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Dextrans
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Polymers
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Polylysine
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Heparin
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Chondroitin Sulfates