FR-900130, a novel amino acid antibiotic. II. Isolation and structure elucidation of the acetyl derivative of FR-900130

Y Kuroda; M Okuhara; T Goto; M Kohsaka; H Aoki; H Imanaka

doi:10.7164/antibiotics.33.132

FR-900130, a novel amino acid antibiotic. II. Isolation and structure elucidation of the acetyl derivative of FR-900130

J Antibiot (Tokyo). 1980 Feb;33(2):132-6. doi: 10.7164/antibiotics.33.132.

Authors

Y Kuroda, M Okuhara, T Goto, M Kohsaka, H Aoki, H Imanaka

PMID: 7380723
DOI: 10.7164/antibiotics.33.132

Abstract

FR-900130 is a new antibiotic having an acetylene moiety and is very unstable in aqueous solution. The antibiotic was isolated as the acetyl derivative by ion-exchange resin and adsorption chromatography. The structure has been determined to be L-2-amino-3-butynoic acid by spectral data of its derivatives.

MeSH terms

Acetylation
Aminobutyrates / analysis
Aminobutyrates / isolation & purification
Anti-Bacterial Agents / analysis*
Anti-Bacterial Agents / isolation & purification
Chemical Phenomena
Chemistry
Hydrogenation
Methylation

Substances

Aminobutyrates
Anti-Bacterial Agents
acetyl FR-900130
L-2-amino-3-butynoic acid