Retinal and choroidal microvascular embolism after intranasal corticosteroid injection

Am J Ophthalmol. 1980 Jun;89(6):851-3. doi: 10.1016/0002-9394(80)90178-6.

Abstract

Two patients had uniocular visual loss after methylprednisolone acetate (Depo-Medrol) injection for control of chronic inflammatory conditions in the nose. The cause of the visual loss was embolic retinal and choroidal vascular occlusion. The emboli were presumably aggregates of microcrystals of methylprednisolone acetate.

MeSH terms

  • Adult
  • Embolism / complications
  • Embolism / etiology*
  • Ethmoid Sinus
  • Female
  • Humans
  • Injections / adverse effects*
  • Male
  • Methylprednisolone / administration & dosage*
  • Methylprednisolone / adverse effects
  • Nasal Septum*
  • Retinal Artery*
  • Rhinoplasty
  • Vision Disorders / etiology*

Substances

  • Methylprednisolone