The not-so-benign Miller Fisher syndrome: a variant of the Guilain-Barré syndrome

Arch Neurol. 1980 Jun;37(6):384-5. doi: 10.1001/archneur.1980.00500550086016.


Two patients with Fisher's syndrome of ophthalmoplegia, ataxia, and areflexia experienced severe weakness and respiratory distress. Both patients required tracheostomy and assisted ventilation, but both made a complete recovery. Fisher's syndrome is generally considered to be a benign variant of acute infectious polyneuropathy (the Guillain-Barre syndrome). Our two patients demonstrate that the condition is not always benign.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Ataxia / diagnosis*
  • Female
  • Humans
  • Male
  • Ophthalmoplegia / diagnosis*
  • Reflex, Abnormal / diagnosis*
  • Respiration Disorders / diagnosis
  • Syndrome