Psoriasis and HLA-Cw6

Br J Dermatol. 1980 Feb;102(2):179-84. doi: 10.1111/j.1365-2133.1980.tb05690.x.


The prevalence of histocompatibility antigen HLA-Cw6 was 72.7% in twenty-two patients with the guttate form and 45.9% in thirty-seven patients with the vulgaris form of psoriasis; the difference between these figures and the prevalence (7.4%) in 462 healthy blood donors in Finland is highly significant. The previously observed excess of several HLA-B locus genes might be secondary to their close linkage with the Cw6 gene. Hereditary factors appear more important in the guttate than in the vulgaris form of psoriasis.

MeSH terms

  • Finland
  • HLA Antigens / analysis*
  • Humans
  • Psoriasis / genetics
  • Psoriasis / immunology*


  • HLA Antigens