One hundred seventy-two consecutive cases of pure anisometropic amblyopia have been studied. Of them 167 were anisohypermetropic and five of them were anisomyopic. The majority of the cases (65.1%) were teenagers. A difference of 1 to 2 diopters between the two eyes formed the single largest group comprising 28.5% cases. Amblyopia was dense and the fixation was foveal in majority of the cases. Statistical analysis of the data revealed that the age at presentation has no relationship to the degree of anisometropia. The higher the age at presentation the greater is the depth of amblyopia. A higher degree of anisometropia is associated with a more severe degree of amblyopia. Persons with a lesser degree of anisometropia are more likely to have fixation at or near the fovea than persons with higher degree of anisometropia. There is a significant association between the age at presentation and the eccentricity of fixation. The farther the fixation is from the fovea the greater is the loss of vision.