Ocular inflammation in Reiter's disease after Salmonella enteritis

Am J Ophthalmol. 1980 Jul;90(1):63-8. doi: 10.1016/s0002-9394(14)75077-9.


We studied characteristics of ocular inflammation in Reiter's disease after Salmonella enteritis in eight patients. After an acute onset with diarrhea, fever in six patients, and headache in three patients, all patients developed arthritis; six patients had myalgia; six patients, urethritis; and one patient, carditis. Sacroiliitis was found in four patients. All patients had HLA-B28 antigen. Conjunctivitis occurred in seven patients. It was mostly mild with no chemosis, follicles, or keratitis, and resolved in ten days. In one case palpebral edema, chemosis in the conjunctiva, and purulent exudate were seen. One patient had transient episodes of keratitis and corneal erosion for two months and episodes of conjunctivitis for 11 months. Three patients developed unilateral acute anterior uveitis with aqueous flare, cells, fine keratic precipitates, and fibrinous exudation from three to four years after the onset of the illness. One of these patients had vitritis and macular and papillary edema.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Arthritis / etiology
  • Arthritis, Reactive / complications*
  • Arthritis, Reactive / diagnosis
  • Arthritis, Reactive / genetics
  • Chloramphenicol / therapeutic use
  • Conjunctivitis / drug therapy
  • Conjunctivitis / etiology
  • Eye Diseases / etiology*
  • Female
  • HLA Antigens / analysis
  • Humans
  • Male
  • Middle Aged
  • Pedigree
  • Salmonella Infections / complications*
  • Salmonella Infections / diagnosis
  • Uveitis / etiology


  • HLA Antigens
  • Chloramphenicol