Transmission of a balanced homologous t(22q;22q) translocation from mother to normal daughter

Clin Genet. 1980 Jun;17(6):418-22. doi: 10.1111/j.1399-0004.1980.tb00173.x.


The transmission of a t(22q;22q) translocation is reported. The mother had had multiple miscarriages and carried both t(22q;22q) and t(22p;22p) portions of the rearrangement in a portion of her cells. The phenotypically normal daughter, who was the proband and was referred because of multiple miscarriages, also carried the t(22q;22q) translocation.

Publication types

  • Case Reports

MeSH terms

  • Abortion, Habitual / genetics
  • Adult
  • Chromosomes, Human, 21-22 and Y*
  • Female
  • Humans
  • Middle Aged
  • Pedigree
  • Pregnancy
  • Translocation, Genetic*