The metabolism of 8-methoxypsoralen in man

Eur J Drug Metab Pharmacokinet. 1980;5(2):81-92. doi: 10.1007/BF03189450.


8-Methoxypsoralen is metabolized rapidly and completely in man. Most of the metabolites presently known have their origin in a metabolic attack on the furan moiety yielding an aryl-diol and aryl-acetic-acid and are excreted as conjugates.

MeSH terms

  • Biotransformation
  • Chemical Phenomena
  • Chemistry
  • Chromatography, Thin Layer
  • Feces / analysis
  • Humans
  • Hydrolysis
  • Magnetic Resonance Spectroscopy
  • Mass Spectrometry
  • Methoxsalen / metabolism*
  • Methoxsalen / urine
  • Spectrophotometry, Ultraviolet


  • Methoxsalen