Direct injection of methylprednisolone sodium succinate in the treatment of solitary eosinophilic granuloma of bone: a report of 9 cases

Radiology. 1980 Aug;136(2):289-93. doi: 10.1148/radiology.136.2.7403498.


Solitary eosinophilic granulomas of bone are benign and tend to heal spontaneously over a period of months to years. Radiotherapy and curettage have certain risks, which may be excessive considering the benign nature of the lesion. The authors injected methylprednisolone directly into 9 pathologically proved solitary eosinophilic granulomas of bone and obtained initiation of healing and relief of pain in 8. There were no complications.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Bone Diseases / diagnostic imaging
  • Bone Diseases / drug therapy*
  • Child
  • Child, Preschool
  • Eosinophilic Granuloma / diagnostic imaging
  • Eosinophilic Granuloma / drug therapy*
  • Femur
  • Follow-Up Studies
  • Humans
  • Injections
  • Mandible
  • Methylprednisolone / administration & dosage*
  • Radiography
  • Scapula
  • Tibia


  • Methylprednisolone