The use of stereoisomers in patch testing

Ann Allergy. 1980 Aug;45(2):100-3.


A patient is described with a clinical picture resembling that of relapsing scarlatina. The complaints were found to be based on two types of delayed-type allergy: one to the equatorially bound hydroxyl grouip at the 6 position of the basic phenanthrene structure as occurs in morphine and codeine, and the other to the D(-)-alpha-position of the amino group as occurs in some penicillin derivatives.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Drug Hypersensitivity / diagnosis*
  • Female
  • Humans
  • Penicillins / adverse effects
  • Phenanthrenes / adverse effects
  • Scarlet Fever / diagnosis*
  • Skin Tests*
  • Stereoisomerism


  • Penicillins
  • Phenanthrenes