Pregnancy outcome for women working in laboratories in some of the pharmaceutical industries in Sweden

Scand J Work Environ Health. 1980 Jun;6(2):131-4. doi: 10.5271/sjweh.2623.


The pregnancy outcome of laboratory employees in three pharmaceutical in Sweden studied with interviews, postal questionnaires, and register studies. The total material shows only a slightly increased miscarriage rate and normal perinatal mortality and malformation rates. Subdivision into two types of laboratory work, "chemical" and "other," revealed a significant difference, with an increased perinatal death rate and an increased rate of major malformations in the chemical group. This observation supports earlier findings indicating that work during pregnancy in a chemical laboratory can represent a hazard to the fetus.

MeSH terms

  • Abnormalities, Drug-Induced
  • Abortion, Spontaneous / chemically induced
  • Chemistry, Pharmaceutical
  • Congenital Abnormalities / epidemiology*
  • Drug Industry*
  • Female
  • Fetal Death / chemically induced
  • Fetal Death / epidemiology*
  • Humans
  • Infant Mortality
  • Infant, Newborn
  • Laboratories*
  • Occupational Diseases / chemically induced
  • Occupational Medicine*
  • Pregnancy Complications / epidemiology*
  • Pregnancy Complications / etiology
  • Pregnancy*
  • Sweden