Abstract
A stereospecific binding site for nicotine has been detected on rat brain membranes. Competition studies with cholinergic agonists suggest that this site is a nicotinic cholinergic receptor.
Publication types
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Animals
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Binding, Competitive
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Brain / metabolism*
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Ligands
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Male
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Nicotine / metabolism
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Rats
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Receptors, Cholinergic / metabolism*
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Receptors, Nicotinic / metabolism*
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Stereoisomerism
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Structure-Activity Relationship
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Synaptic Membranes / metabolism
Substances
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Ligands
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Receptors, Cholinergic
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Receptors, Nicotinic
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Nicotine