Neonatal birch-pollen contact and subsequent allergy to birch pollen

Clin Allergy. 1980 Sep;10(5):585-91. doi: 10.1111/j.1365-2222.1980.tb02140.x.


It is shown by regression analysis that the risk of immediate hypersensitivity to birch pollen, as measured by a skin test, is positively correlated with the quantity of birch male flowers and the number of non-rainy days in the first birch flowering season (May) met in infancy. The risk is also dependent on the month of birth, with maximal risk associated with birth in February--April. The results suggest that early pollen contacts, particularly during the first 6 months of life, increase the risk of pollen allergy for a period of 20 years. We estimate that elimination of early birch pollen contacts could have reduced the prevalence of immediate hypersensitivity to birch by 28% in our age gorup 0--19 years.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Child
  • Child, Preschool
  • Female
  • Humans
  • Hypersensitivity / etiology*
  • Hypersensitivity, Immediate / etiology
  • Infant
  • Infant, Newborn
  • Male
  • Mathematics
  • Pollen*
  • Risk
  • Seasons
  • Skin Tests
  • Trees