Sotos syndrome with intestinal polyposis and pigmentary changes of the genitalia

Clin Genet. 1980 Dec;18(6):413-6. doi: 10.1111/j.1399-0004.1980.tb01785.x.


We report two adult males with the Sotos syndrome, who also presented intestinal polyposis and pigmentary spotting of the shaft and glans penis. We propose that patients with the Sotos syndrome may develop hamartoneoplastic disease and we urge clinicians to consider this possibility in those patients.

Publication types

  • Case Reports

MeSH terms

  • Abnormalities, Multiple / complications*
  • Adult
  • Bone and Bones / abnormalities
  • Hamartoma / complications*
  • Humans
  • Intellectual Disability / complications
  • Intestinal Polyps / complications*
  • Male
  • Penis
  • Pigmentation Disorders / complications*
  • Skull / abnormalities*
  • Syndrome