Dapsone in the treatment of lupus erythematosus

Br J Dermatol. 1981 Jan;104(1):53-6. doi: 10.1111/j.1365-2133.1981.tb01711.x.


Dapsone yielded excellent therapeutic results in certain forms of lupus erythematosus (LE), whereas discoid lesions and the maculo-papular rash of the systemic and disseminated chronic forms of discoid LE remained uninfluenced by the drug. On the basis of these observations, we suggest the following indications for dapsone treatment in LE: (1) Vasculitic urticaria. (2) Oral ulceration. (3) Non-scarring form of chronic LE. (4) Chloroquine intolerance.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Child
  • Dapsone / therapeutic use*
  • Female
  • Humans
  • Lupus Erythematosus, Discoid / drug therapy*
  • Lupus Erythematosus, Systemic / drug therapy*
  • Male


  • Dapsone