Leukocyte chemotaxis in recurrent polyserositis (familial Mediterranean fever)

Am J Med Sci. Jan-Feb 1981;281(1):15-8. doi: 10.1097/00000441-198101000-00002.

Abstract

Polymorphonuclear leukocyte chemotaxis was investigated in 35 patients with recurrent polyserositis during attacks and during spontaneous or colchicine-induced remissions. Chemotaxis was found to be unchanged in the attack-free period in untreated patients, increased by about 50% during attacks, and decreased by about 50% during colchicine treatment.

MeSH terms

  • Adolescent
  • Adult
  • Chemotaxis, Leukocyte*
  • Child
  • Colchicine / therapeutic use
  • Familial Mediterranean Fever / blood*
  • Familial Mediterranean Fever / drug therapy
  • Female
  • Humans
  • Male
  • Middle Aged
  • Neutrophils

Substances

  • Colchicine