Association of hypertrophic maxillary frenulum with hypoplastic left heart syndrome

J Pediatr. 1995 Nov;127(5):749-50. doi: 10.1016/s0022-3476(95)70167-2.

Abstract

We report a previously unrecognized association between a hypertrophic frenulum separating the alveolar portion of the maxillary palatine suture with hypoplastic left heart syndrome in one fetus and seven children. A hypertrophic frenulum was not found in 25 pediatric cardiology patients without hypoplastic left heart syndrome. This finding may provide a marker for suspecting hypoplastic left heart syndrome in the neonate.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Autopsy
  • Child, Preschool
  • Female
  • Humans
  • Hypertrophy / pathology
  • Hypoplastic Left Heart Syndrome / pathology*
  • Infant
  • Karyotyping
  • Labial Frenum / pathology*
  • Male
  • Maxilla