Abstract
This article presents the theoretical microbiological principles involved in the pathogenesis of periprosthetic infection, the role of microbiology in diagnosing this disease, and factors requiring special consideration when selecting topical antibiotics. It also describes the operative technique of one-stage exchange arthroplasty using antibiotic-loaded acrylic cement and the results achieved with this method to date.
MeSH terms
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Activities of Daily Living
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Anti-Bacterial Agents / administration & dosage*
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Bone Cements / therapeutic use
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Debridement / methods
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Gait
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Hip Prosthesis*
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Humans
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Methylmethacrylates / administration & dosage
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Microbiological Techniques
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Prosthesis-Related Infections / drug therapy
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Prosthesis-Related Infections / microbiology
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Prosthesis-Related Infections / surgery*
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Reoperation / methods
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Therapeutic Irrigation / methods
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Treatment Outcome
Substances
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Anti-Bacterial Agents
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Bone Cements
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Methylmethacrylates