Consumption of a garlic clove a day could be beneficial in preventing thrombosis

Prostaglandins Leukot Essent Fatty Acids. 1995 Sep;53(3):211-2. doi: 10.1016/0952-3278(95)90118-3.


The effect of the consumption of a fresh clove of garlic on platelet thromboxane production was examined. A group of male volunteers in the age range 40-50 years participated in the study. Each volunteer consumed one clove (approximately 3 g) of fresh garlic daily for a period of 16 weeks. Each participant served as his own control. Thromboxane B2 (TXB2, a stable metabolite of thromboxane A2), cholesterol and glucose were determined in serum obtained after blood clotting. After 26 weeks of garlic consumption, there was an approximately 20% reduction of serum cholesterol and about 80% reduction in serum thromboxane. No change in the level of serum glucose was observed. Thus, it appears that small amounts of fresh garlic consumed over a long period of time may be beneficial in the prevention of thrombosis.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Blood Glucose / metabolism
  • Blood Platelets / metabolism*
  • Cholesterol / blood
  • Garlic*
  • Humans
  • Male
  • Middle Aged
  • Plants, Medicinal*
  • Thrombosis / prevention & control*
  • Thromboxane B2 / blood*


  • Blood Glucose
  • Thromboxane B2
  • Cholesterol