Reproducibility of quantitative, spirometrically controlled CT

Radiology. 1995 Nov;197(2):539-42. doi: 10.1148/radiology.197.2.7480708.


Quantitative spirometrically controlled computed tomography (with 1-mm-thick sections) was performed twice (with a 5-minute break) in 24 adult patients with pulmonary disease to objectively evaluate parenchymal changes in the lung. Twelve measurements of attenuation were made on apical, carinal, and basal scans (right, left, total of each level, total right, total left, total of all three scans), obtained at 50% vital capacity. Since differences in measurements between the first and second examination were not significant, the method provides highly reproducible results.

MeSH terms

  • Adult
  • Aged
  • Equipment Design
  • Female
  • Humans
  • Image Enhancement / methods
  • Image Processing, Computer-Assisted
  • Lung Diseases / diagnostic imaging*
  • Male
  • Middle Aged
  • Pulmonary Fibrosis / diagnostic imaging
  • Pulmonary Ventilation
  • Reproducibility of Results
  • Respiration
  • Sarcoidosis / diagnostic imaging
  • Scleroderma, Localized / diagnostic imaging
  • Spirometry* / instrumentation
  • Tomography, X-Ray Computed* / instrumentation
  • Tomography, X-Ray Computed* / methods
  • Vital Capacity
  • alpha 1-Antitrypsin Deficiency