The penis as a vascular organ. The importance of corporal smooth muscle tone in the control of erection

Urol Clin North Am. 1995 Nov;22(4):727-45.


The intrinsic biological complexity of penile erection and the multifaceted nature of erectile dysfunction are just beginning to be fully appreciated. This article describes how mechanistic studies of the local control of penile erection, with specific emphasis on the primary role of the corporal smooth muscle, contribute to the improved understanding, diagnosis, and treatment of erectile dysfunction.

Publication types

  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Humans
  • Impotence, Vasculogenic / drug therapy
  • Impotence, Vasculogenic / etiology
  • Impotence, Vasculogenic / physiopathology
  • Male
  • Muscle Tonus / drug effects
  • Muscle Tonus / physiology*
  • Muscle, Smooth / blood supply*
  • Muscle, Smooth / drug effects
  • Muscle, Smooth / physiology
  • Penile Erection / drug effects
  • Penile Erection / physiology*
  • Penis / blood supply*
  • Penis / drug effects
  • Penis / physiology