Intracavernous injection therapy for male erectile dysfunction

Urol Clin North Am. 1995 Nov;22(4):833-45.


Intracavernosal injection therapy has consistently produced erections in 60% to 70% of patients in whom it is tried. About 70% of patients enter long-term therapy and there is a dropout rate of 20% to 50% within the first year. The most effective current regimen is a mixture of papaverine-phentolamine and prostaglandin E1, that also seems to have a relatively low incidence of priapism and fibrous nodule formation. Patient education is vitally important to the success of a program. Patient satisfaction rates are high.

Publication types

  • Review

MeSH terms

  • Drug Therapy, Combination
  • Erectile Dysfunction / drug therapy*
  • Erectile Dysfunction / physiopathology
  • Humans
  • Injections
  • Male
  • Patient Education as Topic
  • Penile Erection / drug effects*
  • Penile Erection / physiology
  • Penis
  • Self Care
  • Treatment Outcome