Effect of paroxetine on seizure length during electroconvulsive therapy

Acta Psychiatr Scand. 1995 Sep;92(3):239-40. doi: 10.1111/j.1600-0447.1995.tb09576.x.

Abstract

This study reports the effect of paroxetine, a selective serotonin reuptake inhibitor, on seizure length during electroconvulsive therapy. Seven inpatients taking paroxetine were compared with 7 controls taking tricyclic antidepressants. The mean seizure length of the paroxetine group was approximately twice that of the control group.

Publication types

  • Comparative Study

MeSH terms

  • Adult
  • Aged
  • Antidepressive Agents, Tricyclic / adverse effects
  • Antidepressive Agents, Tricyclic / therapeutic use
  • Combined Modality Therapy
  • Depressive Disorder / psychology
  • Depressive Disorder / therapy*
  • Dose-Response Relationship, Drug
  • Electroconvulsive Therapy*
  • Electroencephalography / drug effects*
  • Female
  • Humans
  • Male
  • Middle Aged
  • Paroxetine / adverse effects
  • Paroxetine / therapeutic use*
  • Serotonin Uptake Inhibitors / adverse effects
  • Serotonin Uptake Inhibitors / therapeutic use*

Substances

  • Antidepressive Agents, Tricyclic
  • Serotonin Uptake Inhibitors
  • Paroxetine