Relation of duration of morbid obesity to left ventricular mass, systolic function, and diastolic filling, and effect of weight loss

Am J Cardiol. 1995 Dec 1;76(16):1194-7. doi: 10.1016/s0002-9149(99)80338-5.


Longer duration of morbid obesity is associated with higher LV mass, poorer LV systolic function, and greater impairment of LV diastolic filling. Weight loss-induced decreases in LV mass and improvements in LV systolic function and diastolic filling are due in part to favorable alterations in LV loading conditions.

MeSH terms

  • Adult
  • Blood Pressure
  • Diastole
  • Echocardiography
  • Female
  • Heart Ventricles / pathology
  • Heart Ventricles / physiopathology
  • Humans
  • Male
  • Myocardial Contraction
  • Obesity, Morbid / pathology
  • Obesity, Morbid / physiopathology*
  • Time Factors
  • Ventricular Function, Left*
  • Weight Loss*