Dual second-messenger pathways in olfactory transduction

Curr Opin Neurobiol. 1995 Aug;5(4):461-6. doi: 10.1016/0959-4388(95)80006-9.


Increasing evidence indicates that inositol phosphate as well as cyclic nucleotide signalling pathways mediate olfactory transduction. Both pathways can target multiple ion channel effectors, suggesting that olfactory receptor cells serve as more than simple selectivity filters and that they possibly represent the first stage of olfactory integration.

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.
  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Animals
  • Cyclic AMP / physiology
  • Humans
  • Second Messenger Systems / physiology*
  • Signal Transduction / physiology*
  • Smell / physiology*


  • Cyclic AMP