Polyposis: the Peutz-Jeghers syndrome

Br J Surg. 1995 Oct;82(10):1311-4. doi: 10.1002/bjs.1800821006.


The classical pigmentation of Peutz-Jeghers syndrome distinguishes it immediately from the other polyposis syndromes. Less widely appreciated than this most obvious manifestation are the pitfalls in management presented by the risk of cancer and by the performance of multiple laparotomies that also characterize this condition. An outline of these risks and an approach that minimizes them is presented.

Publication types

  • Review

MeSH terms

  • Diagnosis, Differential
  • Humans
  • Neoplasms / diagnosis
  • Peutz-Jeghers Syndrome* / diagnosis
  • Peutz-Jeghers Syndrome* / pathology
  • Peutz-Jeghers Syndrome* / surgery