SNAREs and the specificity of transport vesicle targeting

Curr Opin Cell Biol. 1995 Aug;7(4):581-6. doi: 10.1016/0955-0674(95)80016-6.


The fidelity of membrane trafficking is mediated by specific interactions between transport vesicles and their target membranes. SNAREs (SNAP receptors) are cytoplasmically oriented membrane proteins that form complexes implicated in transport vesicle targeting. Advances in the past year have provided insight into the fundamental mechanisms underlying the formation, regulation, and function of SNARE complexes.

Publication types

  • Review

MeSH terms

  • Animals
  • Biological Transport
  • Humans
  • Membrane Proteins / physiology*
  • Nerve Tissue Proteins / physiology*
  • SNARE Proteins
  • Synaptic Vesicles / physiology*
  • Vesicular Transport Proteins*


  • Membrane Proteins
  • Nerve Tissue Proteins
  • SNARE Proteins
  • Vesicular Transport Proteins