Histopathology of transgenic mouse mammary tumors (a short atlas)

Semin Cancer Biol. 1995 Jun;6(3):153-8. doi: 10.1006/scbi.1995.0020.


Mammary hyperplasias, dysplasias and tumors have been described in many strains of transgenic mice. Many of the transgenes produce characteristic disturbances of growth, development and neoplasia. The disturbances can now be classified into groups. A classification of transgenic tumors and an atlas illustrating some characteristic examples of common morphological changes in transgenic mammary tissues is provided.

Publication types

  • Comparative Study

MeSH terms

  • Animals
  • Hyperplasia / pathology
  • Mammary Glands, Animal / pathology
  • Mammary Neoplasms, Experimental / genetics*
  • Mammary Neoplasms, Experimental / pathology*
  • Mammary Neoplasms, Experimental / virology
  • Mice
  • Mice, Transgenic
  • Tumor Virus Infections / pathology