Correlates of high-density lipoprotein cholesterol in Black girls and White girls: the NHLBI Growth and Health Study

Am J Public Health. 1995 Dec;85(12):1698-702. doi: 10.2105/ajph.85.12.1698.


To determine the correlates of serum high-density lipoprotein cholesterol (HDL-C) in 9- and 10-year-old girls, data were examined from 624 Black girls and 773 White girls. Black girls had, on average, 3.6 mg/dL higher levels than White girls. Each 10-mm increase in sum of skinfolds was associated with a decrease of 1.4 mg/dL; each unit increase in the tricep/suprailiac skinfold ratio was associated with an increase of 2 mg/dL; and each 10% increase in polyunsaturated fat intake was associated with an increase of 3.4 mg/dL. The associations of sedentary activity and sexual maturation with HDL were mediated by differences in adiposity. Interventions to decrease adiposity may be important for the primary prevention of heart disease in women.

Publication types

  • Comparative Study
  • Multicenter Study
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • African Continental Ancestry Group*
  • Child
  • Cholesterol, HDL / blood*
  • Coronary Disease / etiology
  • Dietary Fats / administration & dosage
  • European Continental Ancestry Group*
  • Exercise
  • Fatty Acids, Unsaturated / administration & dosage
  • Female
  • Humans
  • Obesity / blood*
  • Obesity / complications
  • Obesity / ethnology*
  • Prospective Studies
  • Puberty
  • Risk Factors
  • Skinfold Thickness
  • United States


  • Cholesterol, HDL
  • Dietary Fats
  • Fatty Acids, Unsaturated