Neurodevelopmental profile at five years of children born at < or = 32 weeks gestation

Dev Med Child Neurol. 1993 Dec;35(12):1083-96. doi: 10.1111/j.1469-8749.1993.tb07926.x.


Sixty children born preterm (gestational age < or = 32 weeks) and 60 control children matched by sex, and socio-economic and educational status of the parents were followed prospectively to the age of five years. Neurodevelopmental problems were surveyed by a detailed neurological and neuropsychological test battery, and by ophthalmological and hearing examinations. All except one of the preterm children with major disability had motor, visual-spatial and visual problems. The most frequent neurodevelopmental abnormalities encountered among preterm children without major disability were motor problems--emerging as gross and fine motor and/or visual-motor difficulties--and visual-spatial problems. Language difficulties were not associated with hearing problems. Among those without major disability, visual-spatial difficulties and ophthalmological problems seldom emerged simultaneously.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Audiometry
  • Developmental Disabilities / diagnosis*
  • Educational Status
  • Female
  • Follow-Up Studies
  • Humans
  • Infant, Newborn
  • Infant, Premature / growth & development*
  • Male
  • Nervous System / growth & development*
  • Neurologic Examination
  • Neuropsychological Tests
  • Parents
  • Prospective Studies
  • Socioeconomic Factors
  • Vision Tests